David Kupfer Selected Research

alpha-hydroxytamoxifen

10/2005

Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin.

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David Kupfer Research Topics

Disease

3	Bipolar Disorder (Manic Depressive Psychosis) 03/2010 - 06/2003
2	Mental Disorders (Mental Disorder) 10/2016 - 03/2010
2	Inflammation (Inflammations) 06/2015 - 09/2013
2	Breast Neoplasms (Breast Cancer) 10/2005 - 11/2003
1	Pediatric Crohn's disease 06/2015
1	Schizophrenia (Dementia Praecox) 01/2014
1	Psychotic Disorders (Schizoaffective Disorder) 01/2014
1	Cognitive Dysfunction 01/2014
1	Abdominal Pain (Pain, Abdominal) 09/2013
1	Neoplasms (Cancer) 04/2013
1	Arthritis (Polyarthritis) 04/2013
1	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 03/2010

Drug/Important Bio-Agent (IBA)

3	Biomarkers (Surrogate Marker)IBA 10/2016 - 04/2013
1	SteroidsIBA 06/2015
1	Prednisolone (Predate)FDA LinkGeneric 01/2014
1	Antipsychotic Agents (Antipsychotics)IBA 01/2014
1	Biological ProductsIBA 03/2010
1	afimoxifene (hydroxytamoxifen)IBA 10/2005
1	N-desmethyltamoxifenIBA 10/2005
1	tamoxifen N-oxideIBA 10/2005
1	alpha-hydroxytamoxifenIBA 10/2005
1	Tamoxifen FDA LinkGeneric 10/2005
1	LithiumIBA 05/2005
1	Pharmaceutical PreparationsIBA 05/2005
1	SteamIBA 05/2005
1	Estrogens (Estrogen)FDA Link 11/2003
1	Estradiol (Delestrogen)FDA LinkGeneric 11/2003
1	Methoxychlor (Metox)IBA 11/2003
1	GenisteinIBA 11/2003
1	CoumestrolIBA 11/2003

Therapy/Procedure

1	Therapeutics 10/2005
1	Secondary Prevention 06/2003